Available Technology
In Vitro Nanomaterial Toxicity Assay
Technology:
Method for measuring the effective density of engineered nanomaterials in liquid suspensions: Implications for in vitro dosimetry and nanotoxicology
Markets Addressed
The technology offered here provides a simple method to empirically measure effective density and agglomeration potential of engineered nanomaterials (carbon nanotubes, nanowires etc) in physiologic fluids and other liquids. Engineered nanomaterials, which have widely entered the consumer market in recent years, have been the subject of controversy in terms of their environmental health and safety. Current in-vitro screening tests for nanotoxicology often fail to take into account engineered nanomaterial transformations and agglomeration which occur while in suspension as well as the subsequent effects on the particle interaction with adherent cells.
Innovations and Advantages
This technique overcomes existing systems’ limitations providing (potentially the first) efficient, accurate and inexpensive method to measure effective density and agglomeration potential of engineered nanomaterials with implications in nanotoxicology and nano-bio interactions.
Additional Information
Intellectual Property Status: Patent(s) pending
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Inventor(s):
Cohen, Joel
DeLoid, Glen
Demokritou, Philip
Categories:
For further information, please contact:
Alan Gordon, Director of Business Development
(617) 384-5000
Reference Harvard Case #4545