Available Technology
Laser-induced photobiomodulation for dentin regeneration
Technology:
Based on elucidation of the molecular mechanisms triggered by low-power lasers, scientists at the Mooney lab, designed a product that combines a protocol along with dedicated consumables, and is harnessed to evoke direct differentiation and proliferation of dentin.
Markets Addressed
Although high power lasers are used routinely for surgical incisions and low power lasers have anecdotal reports of their clinical use, the potential for low power lasers in the clinic has been limited by utility. Recent research out of Harvard University’s School of Engineering and Applied Science show that the use of low power lasers in a specific proprietary protocol stimulates tissue regeneration via a TGF-β mediated pathway.
Innovations and Advantages
Current development continues using this laser-mediated growth factor mechanism to specifically drive the differentiation of odontogenic cells to form mineralized tissues. A laser device that automatically delivers the Harvard protocol in combination with a proprietary consumable to be used to induce dentin regeneration is in development, with the ideal clinical context being pulp capping and tooth desensitization.
Additional Information
A provisional patent application for this technology has been filed. This technology is available for worldwide, exclusive licensing and/or a collaborative research program
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Inventor(s):
Arany, Praveen
Mooney, David J.
Categories:
For further information, please contact:
Laura Brass, Director of Business Development
(617) 495-3067
Reference Harvard Case #3510