Available Technology
Oligopaints as a means for marking chromosomes with superior resolution and labeling functionality
Technology:
Oligopaints
Markets Addressed
Oligopaints have the potential to be of significant interest to chromosome paint / karyotyping users in the basic and medical sciences as well as in clinical setting and may ultimately enable the development of next generation DNA-based diagnostics.
Innovations and Advantages
Oligopaints could provide a means for marking chromosomes with superior resolution and labeling functionality than currently commercially available chromosome paint alternatives. In addition, the technology may be applied to any organism for which there is a genome sequence. The Oligopaint technology could provide for more flexible customization (e.g., user can choose which fluors, which chromosomal regions to paint, which DNA strand to mark) while potentially avoiding background issues caused by repetitive sequences. The Oligopaint technology may open new channels of investigation to chromosome biology and potentially to next-generation diagnostics based on high-resolution karyotyping.
Additional Information
Intellectual Property Status: Patent(s) pending
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Inventor(s):
Church, George M.
Williams, Benjamin Richard
Wu, Chao-ting
Categories:
For further information, please contact:
Maryanne Fenerjian, Director of Business Development
(617) 432-0920
Reference Harvard Case #3495