Available Technology
Monoclonal IgE anti-ovalbumin antibody
Technology:
Monoclonal Ig E mouse anti-ovalbumin
Markets Addressed
Currently there is no commercial IgE anti-ova available that could be useful as a positive control in ELISA assays which measure the level of IgE anti-ovalbumin antibodies in mouse models of asthma. Most investigators use a pool of positive serum as the positive control and express their results as an index. This reagent could be of interest to many asthma and immunology investigators.
Innovations and Advantages
A laboratory from the Harvard School of Public Health has developed a monoclonal Ig E mouse anti-ovalbumin. This antibody is useful as a positive control in ELISA assays used to measure the level of IgE anti-ovalbumin antibodies in mouse models of asthma. An IgG1 mouse anti-ovalbumin hybridoma is also available.
Additional Information
Publication:
-Characterization of this monoclonal was described in the article titled "Allergen-Independent Maternal Transmission of Asthma Susceptibility," Journal of Immunology, 2003, 170:1683-1689.
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Inventor(s):
Kobzik, Lester
Palecanda, Aiyappa M.
Categories:
For further information, please contact:
Debra Peattie, Director of Business Development
(617) 495-3067
Reference Harvard Case #2203