Available Technology
Absolute quantification of Proteins (AQUA)
Technology:
Reagents, kits, and methods for accurate quantification of proteins and methods for use
Markets Addressed
The invention provides reagents, kits, and methods for accurate quantification of proteins and methods for use. The reagents, kits, and methods of the invention are useful for rapid, high throughput analysis of proteomes.
Innovations and Advantages
This invention provides methods, reagents and kits for obtaining absolute quantification of proteins and their modifications directly from cell lysates. In particular, the invention provides peptide internal standards for use in high performance liquid chromatography (HPLC) with online detection by multistage mass spectrometry (MSn).
Additional Information
Intellectual Property Status: Issued U.S. patent nos.: 7,501,286
Licenses available on a non-exclusive basis.
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Inventor(s):
Gerber, Scott A.
Gygi, Steven P.
Categories:
For further information, please contact:
Grant Zimmermann, Director of Business Development
(617) 495-3067
Reference Harvard Case #1918