Available Technology
Sensitive assay to identify inhibitors of HSV DNA polymerase
Technology:
Antiviral screening assay
Markets Addressed
This high throughput antiviral screening assay has utility in identification of small molecule candidates for DNA viruses.
Innovations and Advantages
Investigators from Harvard Medical School have developed a novel in vitro screening assay for small molecule inhibitors of viral DNA polymerase subunits. A number of hit have been identified with this assay that show antiviral effect in the low micromolar range, and the activity profiles of the in vitro assay itself correspond well to the antiviral effect.
Additional Information
Intellectual Property Status: Issued U.S. patent nos.: 7,132,231
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Inventor(s):
Coen, Donald M.
Pilger, Beatrice O.
Categories:
For further information, please contact:
Grant Zimmermann, Director of Business Development
(617) 495-3067
Reference Harvard Case #1903