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AVAILABLE TECHNOLOGIES - Oncology

Results: 36
Case # Lead Inventor Title
4768Haigis, Marcia C.Inhibiting long chain fatty acid oxidation for the treatment of cancer
4717Wagner, GerhardA fragment based drug discovery platform ; For high throughput synthesis and screening of protein-protein inhibitors
4415Collier, R. JohnKilling tumor cells with a receptor-targeted bacterial toxin
4316Mooney, David J.Controlled delivery of TLR agonists in structural polymeric devices
4188Haigis, Marcia C.Cancer Metabolism: SIRT4 as a Key Regulator of Glutamine Metabolism
4158Aktas, HuseyinSmall molecule modulators of ER Stress: Targeting the eIF2a Ternary Complex
3843Liu, David R.Small-molecule macrocycles: Potent and selective Src kinase inhibitors
3785Haigis, Marcia C.Regulation of hypoxia and glycolysis through modulation of SIRT3 activity: SIRT3 activators for cancer metabolism and SIRT3 inhibitors for vascular disease
3782Mooney, David J.Nanoparticle targeting to ischemia or Cancer for imaging and therapy
3741McMahon, Andrew P.Modulators of hedgehog signaling
3724Brugge, Joan SiefertCombination cancer therapies to circumvent induced resistance pathways
3700Myers, Andrew G.Trioxacarcins and analogs: DNA-modifying compounds with potent anti-proliferative effects
3692Blenis, JohnIdentification of novel downstream effectors of the mTOR1 pathway
3681Artavanis-Tsakonas, SpyrosModulators of notch dimerization and receptor signalling
3569Roth, Frederick P.Novel combination therapies for the treatment of cancer and inflammation
3564Struhl, KevinMetformin selectively targets cancer stem cells
3469Sorger, Peter K.Knockout mouse model for human liver cancer
3439Aktas, HuseyinSmall molecule activators of HRI kinase: A new class of anti-cancer therapeutics and biomarker for cancer patient selection
3438Walker Kahne, SuzannePotent OGT inhibitors for the treatment of cancer and diabetic complications
3358Corey, Elias J.Next generation therapeutics for macular degeneration and cancer
3289Hu, GuofuUse of neamine for treating prostate cancer
3283King, Randall W.Small molecule inhibitor of Cdc20 induces mitotic arrest
3219Myers, Andrew G.Synthetic route for anti-angiogenic natural products cortistatins and analogs
3216Schreiber, Stuart L.Robotnikinin: small molecule inhibitor of sonic hedgehog (Shh) signaling in human cells
3059Bean, Bruce P.Targeting anti-cancer drugs intracellularly via TRP channels
3025Schier, Alexander FRNA therapy: miRNA target protectors
2963Gygi, Steven P.Mass spectrometry-based in vitro kinome activity assay
2438Myers, Andrew G.Natural product avrainvillamide and its analogs as targeted anticancer agents
2193Myers, Andrew G.A novel assay for identifying biological targets of DNA binding agents
2060Schreiber, Stuart L.Anti-mitotic Eg5 inhibitors for the treatment of cancer and inflammatory disease
1742Jones, Alun G.Next generation diagnostics for breast cancer, prostate cancer and melanoma
1659Yuan, Zhi-MinNovel means of protecting the cell against oncogenic tumor formation
1653Yuan, JunyingSmall molecule inhibitors of the Bcl-XL/Bak interaction activate the cell death pathway
1229Howley, Peter M.Gene therapy for papillomavirus induced cervical carcinoma
1188Wong, David T. W.Novel tumor suppressor protein and gene could be used to develop treatments of carcinoma
1083Kassis, Amin I.Rapid Synthesis of Radiolabeled Pyrimidine Nucleosides or Nucleotides for Tumor or Lesion Imaging