Funded Projects
Accelerator Funded Projects: 2007-2011:
| Principal Investigator(s) (School) | Project Name | Year of Award |
|---|---|---|
| Halperin, Jose and Wagner, Gerhard (HMS) | Inhibitors of Translation Initiation for Cancer Therapy | FY08 |
| Harrison, Stephen (HMS) | Small Molecule Viral Entry Inhibitors That Target HIV | FY08 |
| Myers, Andrew (FAS) | Anticancer Agent Based on the Natural Product Avrainvillamide | FY08 |
| Sharpe, Arlene (HMS) | Pd-1 Small Molecule Immune Response Screening for Treatment of MS, Diabetes and Infection | FY08 |
| Silver, Pamela (HMS) | Quantitatively Designed Protein Therapeutics for Cancer | FY08 |
| Walker, Suzanne (HMS) | Development of O-GlcNAc Transferase Inhibitors for Treatment of Diabetes | FY08 |
| Coen, Donald (HMS) | Development of New Anti-Cytomegalovirus Compounds | FY09 |
| Glimcher, Laurie (HSPH) | From Sugar to Fat: The IRE1a XBP1 Signaling Pathway Regulates Hepatic Lipogenesis | FY09 |
| Hu, Guofu (HMS) | Optimization of the Therapeutic Activity of Angiogenin in the Treatment of ALS | FY09 |
| Kahne, Daniel (FAS) | Development of Broad Spectrum Antibiotics for New Targets | FY09 |
| Qin, Xuebin (HMS) | Abrogation of Human CD59 Function for Immune Cancer Therapy | FY09 |
| Ritter, Tobias (FAS) | Late-Stage Fluorination of Biomedically-Active Molecules | FY09 |
| Rubin, Eric (HSPH) | The Clp Protease as a Novel Target for Antibiotics Against Tuberculosis | FY09 |
| Whitman, Malcolm (HSDM) | Design and Testing of Novel Small Molecule Th17 Regulators with Anti-fibrotic Potential | FY09 |
| Xie, Sunney (FAS) | CARS Endoscopy for Biomedicine | FY09 |
| Bernhardt, Thomas (HMS) | Antibacterial Discovery Using a Chemical Suppressor Screen | FY10 |
| Finley, Daniel (HMS) | Small Molecule Inhibitors of the Deubiquitinating Enzymes Usp14 and Uch37 | FY10 |
| Haigis, Marcia (HMS) | Identification of SIRT4 Inhibitors to Stimulate Fatty Acid Catabolism | FY10 |
| Halperin, Jose (HMS) | Glycated CD59 as a Biomarker of Impaired Glucose Tolerance (Pre-Diabetes) | FY10 |
| Hotamisligil, Gokhan (HSPH) | Development of a Therapeutic Antibody Against Diabetes and Related Metabolic Diseases | FY10 |
| Lory, Stephen (HMS) | Development of Antimicrobial Agents Targeting Bacterial Cell Envelope Biogenesis | FY10 |
| Yuan, Junying (HMS) | Development of Autophagy Inhibitors for Cancers and Acute Pancreatitis | FY10 |
| Beckwith, Jon (HMS) | One Screen for Inhibitors of Both Major Disulfide Bond Formation Pathways used by Bacterial Pathogens | FY11 |
| Flanagan, John (HMS) | Design and Testing of a New Approach to Promote CNS Axon Regeneration | FY11 |
| McMahon, Andy (FAS) and Rubin, Lee (FAS) | Smoothened Inhibitors for Cancer Therapy | FY11 |
| Losick, Rich (FAS) and Kolter, Roberto (HMS) | Developing D-Amino Acids as Anti-Biofilm Drugs | FY11 |
| Von Andrian, Uli (HMS) | Using Tolerogenic Dendritic Cells to Treat Autoimmune Disorders | FY11 |