| Indication |
Product |
Pre-clinical |
Phase I |
Phase II |
Phase III |
Market |
| Basal cell carcinoma |
Small molecule |
|
|
|
|
|
| HIV and HTLV |
HIV and HTLV diagnostic assays and reagents |
|
|
|
|
|
| Periodontal defects |
Growth factor-enhanced osteoconductive matrix |
|
|
|
|
|
| Cystic fibrosis carrier assay |
Molecular diagnostics platform utilizing electrochemical detection |
|
|
|
|
|
| Oncology - soft tissue sarcoma, relapsed ovarian cancer |
Synthetic natural product |
|
|
|
|
|
| Warferin sensitivity assay |
Feline vaccine |
|
|
|
|
|
| First application for prostate cancer |
Point-of-care diagnostic platform |
|
|
|
|
Pre-market |
| Duchenne muscular dystrophy |
Solubilized receptor |
|
|
|
|
|
| Cholera |
Live attenuated oral vaccine |
|
|
|
|
|
| Cervical dysplasia |
DNA vaccine |
|
|
|
|
|
| Cervical dysplasia |
Oncolytic virus |
|
|
|
|
|
| IV-administered antibiotic |
Small molecule |
|
|
|
|
|
| Prostate cancer / Graft versus host disease |
Natural product analog |
|
Phase1/2 |
|
|
|
| HSV-2 |
Protein-based vaccine |
|
Phase 1/2a |
|
|
|
| Multiple sclerosis |
Peptide |
|
Phase 1b |
|
|
|
| Multiple myeloma |
Small molecule |
|
|
|
|
|
| Cardiac damage, neurodegeneration |
Peptide |
|
|
|
|
|
| Oncology |
Peptide analogs |
|
|
|
|
|
| Cancer and fetal/prenatal diseases; also autoimmune, immune, kidney, cardiovascular, and neurological disorders |
Diagnostic |
|
|
|
|
|
| Cardiac reperfusion injury; burn injury; transplantation |
Peptide or antibody |
|
|
|
|
|
| Pain |
Small molecule |
|
|
|
|
|
| Infectious disease |
Antibody |
|
|
|
|
|
| Cancer immunotherapy |
Implantable bioactive biopolymer scaffold |
|
|
|
|
|
| Typhoid fever |
Polysaccharide-based vaccine |
|
|
|
|
|
| Periodontal / root canal infections |
Antibiotic-permeated polymer fiber |
|
|
|
|
|
| HSV-2 |
Replication-deficient virus |
|
|
|
|
|
| Nicotine/Smoking cessation |
Synthetic vaccine nanoparticles |
|
|
|
|
|
| Oncology (CTCL, topical) |
Small molecule |
|
|
|
|
|
| Metabolic disorders |
Small molecule |
|
|
|
|
|
| Metabolic disorders |
Small molecule |
|
|
|
|
|
| HBV |
Peptide-based vaccine |
|
|
|
|
|
| Oncology |
Lung cancer diagnostic |
|
|
|
|
|
| Oncology and infectious diseases |
Small molecule |
Discovery |
|
|
|
|
| Cancer, inflammation, autoimmune, neurodegeneration |
Small molecule |
Discovery |
|
|
|
|
| Liver function |
Low-cost, paper-based point-of-care diagnostic tests for the developing world |
Discovery |
|
|
|
|
| Cancer |
Small molecule |
Discovery |
|
|
|
|
| Metabolic disorders |
Small molecule and/or protein |
Discovery |
|
|
|
|
| Oncology |
Small molecule |
Discovery |
|
|
|
|
| Depression |
Small molecule, rapid antidepressant |
Discovery |
|
|
|
|
| Metabolic disorders |
Small molecule |
Discovery |
|
|
|
|
| Metabolic disorders |
Antibody |
Discovery |
|
|
|
|
