Keyword(s): HIV

  1. Victoria D'Souza, PhD

    Structural biology of retroviruses

    The D’Souza laboratory investigates the structural basis of retroviral replication, including the initiation of reverse transcription and translation of viral genes. Understanding the ...

  2. Ronald Desrosiers, PhD

    HIV and AIDS: vaccine; persistent immune response

    Develop new strategies for blunting viral replication and bolstering the immune system’s ability to eradicate viral-infected T-cell reservoirs. 

  3. David Evans, PhD

    HIV infection and AIDS vaccine development

    Investigate new approaches for AIDS vaccine development using SIV infection of non-human primates as a model system.  

  4. Michael Farzan, PhD

    VIRAL ENTRY AND ANTI-VIRAL STRATEGIES Viral Receptors; HIV Therapy; Dengue Virus; SARS; Ebola Virus

    Undertake translational studies geared toward the development of novel peptide mimetic inhibitors of HlV binding to its cell surface receptor, modeled after the CD4 and CCR5 HIV receptor/co-receptor; ...

  5. Robert Paul Johnson, MD

    HIV mechanism of action and new AIDS therapies

    Gene therapy; vaccines

  6. Amitinder Kaur, MD

    AIDS pathogenesis and CMV opportunistic infection: SIV; vaccine; AIDS resistance

    AIDS modeling in non-human primates; reactivation of latent CMV in HIV-infected individuals; innate resistance to SIV-related disease progression.  

  7. Xuebin Qin, MD, PhD

    Immune modulation to treat cancer and viral infections

    CD59, the complement cascade, and disease    

  8. Arlene Sharpe, MD, PhD

    T-cell regulation and disease: chronic viral infection; autoimmunity, tumor immunotherapy, peripheral tolerance

    T cell co-stimulation and its immunoregulatory role in controlling the balance between T cell activation and tolerance.  

  9. Antoine Van Oijen, PhD

    Single molecule imaging for uncovering molecular mechanisms of action: biologic and therapeutic analysis

    Dr. van Oijen’s research utilizes single molecule imaging for uncovering molecular mechanisms of action pertaining to cell fusion of enveloped viruses, DNA replication fork dynamics, and ...

  10. Susan Westmoreland, VMD

    Neuropathology of HIV and SIV infections and AIDS

    Explore the molecular and cellular bases of neuropathologies associated with HIV and SIV infections, including encephalitis and dementia.