Keyword(s): Cell senescence
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David Sinclair, PhD
Sirtuins in aging and disease: calorie restriction; mitochondria; cancer; diabetes
Study sirtuin pathways, their role in multiple diseases and their lifespan extension capabilities.

Research Categories
Sub-categories
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Drug Development: Methodologies
- $1000 genome»
- Antiretrovirals»
- Atherosclerosis»
- Biomarker»
- Cancer drug targets»
- Cardiac function»
- Cell senescence»
- Combination index»
- Combination therapy»
- Combinatorial selectivity»
- Computational modeling»
- Data mining»
- Disease pathway modeling»
- Disease targets»
- Dose prediction»
- Drug specificity»
- dsRNA therapeutics»
- Gene therapy»
- High throughput»
- In silico molecular modeling»
- In vitro biochemical assays»
- Mechanism-based toxicity»
- Mouse models»
- NeuroD»
- Neuropharmacology»
- Non-invasive therapy»
- Patient-specific therapy»
- Personalized medicine»
- Pharmacokinetics»
- Protein and small molecule production»
- Radiotherapy»
- RNAi»
- Targeted therapy»
- Technology development»