Harvard University Office of Technology Development Collaborative Research Opportunity Finder

1. Daniel Finley, PhD

   Ubiquitin-dependent protein degradation and the proteasome: mechanisms and coordination; architecture; role in disease

   Study of proteasome activity and its relationship to diseases caused by proteinopathies.

   

2. Nancy Kleckner, PhD

   Chromosome dynamics across kingdoms

   Investigation of the molecular and physical underpinnings of basic chromosomal processes.

   

3. Andrew McMahon, PhD

   Developmental and Regenerative Biology

   Investigating the molecular and cellular mechanisms regulating development, repair and regeneration of neural, bone and kidney tissues.

   

4. David Sinclair, PhD

   Sirtuins in aging and disease: calorie restriction; mitochondria; cancer; diabetes

   Study sirtuin pathways, their role in multiple diseases and their lifespan extension capabilities.

   

Research Categories

Research Tools and Instrumentation

Therapeutic Discovery Tools and Assays

Sub-categories

1. Research Tools; Animal and Cell Models; Unique Resources

   1. 3-dimensional basement membrane cell cultures»
   2. Adeno-associated virus (AAV)»
   3. Alexa Fluor dyes»
   4. Artificial tether»
   5. Auditory enrichment»
   6. Automated zebrafish screening»
   7. Automation»
   8. Behavior model»
   9. Biocomputational methods»
   10. Bioinformatics»
   11. Brain plasticity»
   12. Brainbow system»
   13. C. elegans»
   14. Ca2+-GFP-Aequorin»
   15. Calcium indicators»
   16. cDNA libraries from single neurons»
   17. cell culture in linear micro-colonies»
   18. Cell-based assays»
   19. Cellular ablation»
   20. Computer-assisted image analysis»
   21. Cryo-Electron Tomography»
   22. Cyanobacteria»
   23. Drosophila»
   24. Drosophila RNAi Screening Center»
   25. Escape behavior»
   26. Escherichia coli (E. coli)»
   27. FACS analysis»
   28. Genetically-encoded biosensor»
   29. Genome mining»
   30. High resolution transcriptome sequencing»
   31. High Throughput Screening»
   32. Human cells»
   33. Insomnia model»
   34. Interactive computer software»
   35. Knockout mouse»
   36. Lab-On-A-Chip»
   37. Mammalian cells»
   38. Microorganism»
   39. Molecular modeling»
   40. Monkey»
   41. Mouse behavior»
   42. Mouse imaging»
   43. Mouse models»
   44. Mouse tumor models»
   45. Multiphoton laser scanning microscopy»
   46. Natural host»
   47. Neuronal recordings»
   48. Non-human primate»
   49. Odor map»
   50. Odor-guided perceptual decision task»
   51. OMP-ChR2 mice»
   52. Optogenetics»
   53. Physics»
   54. Primate Model»
   55. Protein and small molecule production»
   56. Rabies vector»
   57. Recombinant toxins»
   58. Retrogenic mouse»
   59. Retroviral vector»
   60. Reward-based decision making and learning»
   61. Reward-based learning and decision-making assays»
   62. Rhesus macaque»
   63. S. cerevisiae»
   64. S. pombe»
   65. Short and long-term olfactory memory tests»
   66. Sooty mangabey»
   67. SpH mice»
   68. Tissue engineering»
   69. Transcriptome comparisons»
   70. Transgenic mice»
   71. Transgenic mouse»
   72. Transgenic zebrafish»
   73. Video microscopy»
   74. Visual deprivation»
   75. Widefield FCS»
   76. Xenopus tadpoles»
   77. Yeast»
   78. Yeast microbiology»
   79. Zebrafish larvae»
   80. Zebrafish models»

2. Throughput screening

   1. Cancer»
   2. Drosophila»
   3. High throughput RNAi»
   4. High Throughput Screening»
   5. In vitro biochemical assays»
   6. In vivo small molecule screening»
   7. Mammalian cells»
   8. Microarray»
   9. Yeast»