Keyword(s): T-cell

  1. Martin Dorf, PhD

    Molecular signaling in inflammation: TNF; cytokine; autoimmune disease; T-cell

    Investigate the biochemical signaling perturbations elicited by the pro-inflammatory cytokine TNF that serve to modulate the activation of NF-кB, with a focus on TNF receptor-associated factor ...

  2. Robert Paul Johnson, MD

    HIV mechanism of action and new AIDS therapies

    Gene therapy; vaccines

  3. Arlene Sharpe, MD, PhD

    T-cell regulation and disease: chronic viral infection; autoimmunity, tumor immunotherapy, peripheral tolerance

    T cell co-stimulation and its immunoregulatory role in controlling the balance between T cell activation and tolerance.  

  4. Michael Starnbach, PhD

    Bacterial infection and acquired immunity

    T-cell response to bacterial infection, including sexually transmitted chlamydia disease

  5. Ulrich von Andrian, MD, PhD

    Adaptive immunity and leukocyte trafficking: lymphocyte activation; lymphatic system; intravital microscopy

    Study how immunological memory is produced through the orchestration of the adaptive immune response, including initiation, regulatory mechanisms, and immune cell homing to organs; harnessing of this ...

  6. Gerhard Wagner, PhD

    NMR spectroscopy for analyzing protein structure/function relationships; small molecule screening

    Study protein structure and small molecule binding to proteins, using NMR spectroscopy and other complementary methods