Keyword(s): Transcription

  1. Victoria D'Souza, PhD

    Structural biology of retroviruses

    The D’Souza laboratory investigates the structural basis of retroviral replication, including the initiation of reverse transcription and translation of viral genes. Understanding the ...

  2. Adrian Salic, PhD

    Hedgehog signaling and cell-cell communication

    Post-translation modification with cholesterol; regulation of transcription      

  3. Yang Shi, PhD

    Histone demethylation and gene regulation: gene expression; epigenetics; disease

    Studies on lysine-specific demethylases and biochemical and functional aspects of histone demethylation.  

  4. Charles Weitz, MD, PhD

    Biological mechanisms of circadian clocks and their roles in metabolic processes

    Investigate molecular mechanisms of circadian clocks in the brain, retina, and peripheral tissues  

  5. Fred Winston, PhD

    Mechanisms of eukaryotic gene expression in yeast: transcriptional regulation; chromatin structure

    Employs yeast as a model organism to study mechanisms of eukaryotic transcriptional regulation.  

  6. Bruce Yankner, MD, PhD

    Molecular mechanisms of aging and aging-related neurodegenerative diseases

    Explore aging at the molecular level, employing a systems biology approach