Keyword(s): Signal transduction

  1. Howard Berg, PhD

    Bacterial Motility: Motor Response Based on Sensory Input

    The Berg lab studies the motile behavior of bacteria in order to understand how cells sense and respond to changes in their environment. Processing external cues is a problem encountered by ...

  2. John Blenis, PhD

    Signal transduction: nutrient and energy sensing; disease; mTOR; PI3-kinase; Ras

    Explore the diverse yet overlapping intracellular transmission signals propagated by cell surface receptors that respond to extracellular growth factors, environmental conditions, and other ...

  3. Azad Bonni, MD, PhD

    Neuronal cell development; glioblastoma

    Investigate key intracellular signaling pathways in neuronal cell development and maturation as well as in brain tumors such as glioblastoma  

  4. Joan Brugge, PhD

    Epithelial cell biology; mechanisms of breast and ovarian cancer development

    The biology of epithelial cells and tissues, with an emphasis on mammary gland morphogenesis and breast and ovarian cancer  

  5. Martin Dorf, PhD

    Molecular signaling in inflammation: TNF; cytokine; autoimmune disease; T-cell

    Investigate the biochemical signaling perturbations elicited by the pro-inflammatory cytokine TNF that serve to modulate the activation of NF-кB, with a focus on TNF receptor-associated factor ...

  6. Catherine Dulac, PhD

    Molecular and neuronal basis of murine innate social behaviors

    Study neuronal circuits in the mouse involved with pheromone signaling in terms of their development, processing, architecture, and function; investigate the role genomic imprinting role in mammalian ...

  7. Walter Fontana, PhD

    Information biology: principles, limits, and evolution of information processing in molecular systems

    Develop, apply, and establish the concept of programs as models to represent, model, and analyze complex systems of molecular interactions underlying cellular behavior; empirically characterize and ...

  8. Jeremy Gunawardena, PhD

    Experimental and theoretical analysis of signal transduction: EGF signaling, drug efficacy, phosphorylation states, microfluidics, formalized biology language

    Investigate the dynamics of signal transduction, from a mechanistic and practical perspective. Describe at a fundamental level the input/output transformation that connects external signals to ...

  9. Andrew McMahon, PhD

    Developmental and Regenerative Biology

    Investigating the molecular and cellular mechanisms regulating development, repair and regeneration of neural, bone and kidney tissues.

  10. Alexander Schier, PhD

    Zebrafish as a drug profiling model for sleep disorders

    Chronic sleep disturbance is a problem for a significant number of Americans, but the mechanisms that control sleep and wakefulness are largely unknown. The Schier lab is using zebrafish to ...

  11. David Van Vactor, Jr, PhD

    Cell biology of neuronal connectivity: axon guidance; synapse; signaling mechanisms

    Studies on axon guidance and synapse formation in metazoans such as Drosophila that are in many cases directly relevant to mammalian cells.