Keyword(s): Systems Biology

  1. George Church, PhD

    Personal Genome Project

    Genomic DNA Sequencing Technologies; Gene Synthesis; Biofuel

  2. Walter Fontana, PhD

    Information biology: principles, limits, and evolution of information processing in molecular systems

    Develop, apply, and establish the concept of programs as models to represent, model, and analyze complex systems of molecular interactions underlying cellular behavior; empirically characterize and ...

  3. Jeremy Gunawardena, PhD

    Experimental and theoretical analysis of signal transduction: EGF signaling, drug efficacy, phosphorylation states, microfluidics, formalized biology language

    Investigate the dynamics of signal transduction, from a mechanistic and practical perspective. Describe at a fundamental level the input/output transformation that connects external signals to ...

  4. Craig Hunter, PhD

    Biogenesis, Transport, and Function of intercellular RNAs

    Understand how the silencing information of RNAi spreads among cells and transmits to the progeny; Investigate the function of intercellular RNA transporters in nematodes and mice and discover ...

  5. Erin O'Shea, PhD

    Cellular signaling pathways and regulation of gene expression

    Studies of how cells are monitoring the environment and the resulting response via regulation of gene expression in simple model organisms. Investigates the evolution of transcription regulation; ...

  6. Pamela Silver, PhD

    Systems and synthetic biology: gene expression; synthetic proteins; biofuel

    Investigate a wide spectrum of biological phenomena. Starting with gene regulation as a core theme, investigate nuclear spatial architecture, synthetic biology, epigenetics, systems biology, ...

  7. Peter Sorger, PhD

    Systems biology applied to disease mechanisms and drug therapy

    Translate activity-based proteomic data and computational modeling into practical applications for cancer therapies, inflammation studies, and personalized medicine.  

  8. Bruce Yankner, MD, PhD

    Molecular mechanisms of aging and aging-related neurodegenerative diseases

    Explore aging at the molecular level, employing a systems biology approach