Keyword(s): Yeast

  1. Daniel Finley, PhD

    Ubiquitin-dependent protein degradation and the proteasome: mechanisms and coordination; architecture; role in disease

    Study of proteasome activity and its relationship to diseases caused by proteinopathies.

  2. Samara Reck-Peterson, PhD

    Intracellular cargo movement: the role of molecular motors

    Explore the role of dynein in molecular cargo transport

  3. Frederick Roth, PhD

    Genomic and computational analysis of genetic interactions: protein interactions; gene function; humanized yeast and drug screening; DNA sequencing

    Developing experimental and computational technologies for mapping gene and protein interactions.  

  4. David Sinclair, PhD

    Sirtuins in aging and disease: calorie restriction; mitochondria; cancer; diabetes

    Study sirtuin pathways, their role in multiple diseases and their lifespan extension capabilities.

  5. Fred Winston, PhD

    Mechanisms of eukaryotic gene expression in yeast: transcriptional regulation; chromatin structure

    Employs yeast as a model organism to study mechanisms of eukaryotic transcriptional regulation.