Harvard University Office of Technology Development Collaborative Research Opportunity Finder

1. John Blenis, PhD

   Signal transduction: nutrient and energy sensing; disease; mTOR; PI3-kinase; Ras

   Explore the diverse yet overlapping intracellular transmission signals propagated by cell surface receptors that respond to extracellular growth factors, environmental conditions, and other ...

   

2. Craig Hunter, PhD

   Biogenesis, Transport, and Function of intercellular RNAs

   Understand how the silencing information of RNAi spreads among cells and transmits to the progeny; Investigate the function of intercellular RNA transporters in nematodes and mice and discover ...

   

3. Michael Starnbach, PhD

   Bacterial infection and acquired immunity

   T-cell response to bacterial infection, including sexually transmitted chlamydia disease

   

4. Priscilla Yang, PhD

   Host response to viral infection and drug discovery: dengue virus, hepatitis B and C viruses

   Investigate molecular mechanisms of dengue and hepatitis virus infection and replication; perform HTS for viral antagonists to identify host factors and pathways required for dengue virus infection ...

   

Research Categories

Research Tools and Instrumentation

Therapeutic Discovery Tools and Assays

Sub-categories

1. Drug Development: Methodologies

   1. $1000 genome»
   2. Antiretrovirals»
   3. Atherosclerosis»
   4. Biomarker»
   5. Cancer drug targets»
   6. Cardiac function»
   7. Cell senescence»
   8. Combination index»
   9. Combination therapy»
   10. Combinatorial selectivity»
   11. Computational modeling»
   12. Data mining»
   13. Disease pathway modeling»
   14. Disease targets»
   15. Dose prediction»
   16. Drug specificity»
   17. dsRNA therapeutics»
   18. Gene therapy»
   19. High throughput»
   20. In silico molecular modeling»
   21. In vitro biochemical assays»
   22. Mechanism-based toxicity»
   23. Mouse models»
   24. NeuroD»
   25. Neuropharmacology»
   26. Non-invasive therapy»
   27. Patient-specific therapy»
   28. Personalized medicine»
   29. Pharmacokinetics»
   30. Protein and small molecule production»
   31. Radiotherapy»
   32. RNAi»
   33. Targeted therapy»
   34. Technology development»

2. Molecular Techniques and Experimental Approaches

   1. 3-dimensional basement membrane cell cultures»
   2. Atomic resolution»
   3. Automated DNA sequencing»
   4. Biofuel»
   5. Biomarker»
   6. BRET»
   7. Cancer therapy»
   8. Cell cycle arrest»
   9. Chemical detection of cell proliferation»
   10. ChIP»
   11. Chromatin immunoprecipitation»
   12. Computational infrastructure/tools»
   13. Computational modeling»
   14. Conditional targeted cell ablation»
   15. Cross-fire irradiation»
   16. Cryoelectron microscopy»
   17. Cryoelectron tomography»
   18. Data mining»
   19. DNA nanotechnology»
   20. DNA sequencing»
   21. Experimental yeast genetics»
   22. Extinction therapy»
   23. FISH»
   24. Fluorescent imaging of cell proliferation»
   25. Fluorescent In Situ Hybridization»
   26. FRET»
   27. Gene knockdown»
   28. Gene therapy»
   29. Genetic engineering»
   30. Genetic pulldown»
   31. Genetic screen»
   32. Genome mining»
   33. Global molecular profiling»
   34. Heterologous protein expression»
   35. High resolution structure»
   36. High throughput»
   37. Humanized yeast»
   38. Immune reconstitution»
   39. Immunotherapy»
   40. In silico molecular modeling»
   41. Liposome»
   42. Live cell imaging»
   43. Live cells imaging»
   44. luciferase»
   45. Mathematical modeling»
   46. Membrane protein reconstitution»
   47. Methods development»
   48. Microarray»
   49. Microfluidics»
   50. Molecular modeling»
   51. Molecular sensor»
   52. Multiplexing»
   53. Natural products»
   54. NMR spectroscopy»
   55. Optogenetics»
   56. Patch clamping»
   57. Personal genome»
   58. Phenotypic screen»
   59. Polony DNA sequencing»
   60. Probabilistic decision tree»
   61. Radioiodination»
   62. Radionuclide»
   63. Recombinant viral vector»
   64. RNA inhibition»
   65. RNA interference»
   66. RNAi»
   67. Single molecule imaging»
   68. Single-cell measurement»
   69. Single-cycle SIV»
   70. siRNA screen»
   71. Stem cell gene therapy»
   72. Synthetic biology»
   73. Technology development»
   74. Tissue engineering»
   75. Tumor immunotherapy»
   76. Viral entry imaging»
   77. Virus-membrane complex reconstitution»
   78. X-ray crystallography»