Keyword(s): High Throughput Screening

  1. Jon Clardy, PhD

    Isolation and characterization of small molecule natural products; high-throughput screening for novel therapeutics

    Discovering small molecule, natural products and their biology; high throughput screening for small molecule chemicals that interfere with microbial and mammalian cell processes.  

  2. Jose Halperin, MD

    Targeting protein translation for anticancer therapies; CD59 and diabetes

    Employ the preclinical resources of the Laboratory for Translational Research to develop new therapies and diagnostics in oncology and diabetes

  3. Erin O'Shea, PhD

    Cellular signaling pathways and regulation of gene expression

    Studies of how cells are monitoring the environment and the resulting response via regulation of gene expression in simple model organisms. Investigates the evolution of transcription regulation; ...

  4. Frederick Roth, PhD

    Genomic and computational analysis of genetic interactions: protein interactions; gene function; humanized yeast and drug screening; DNA sequencing

    Developing experimental and computational technologies for mapping gene and protein interactions.  

  5. Alexander Schier, PhD

    Zebrafish as a drug profiling model for sleep disorders

    Chronic sleep disturbance is a problem for a significant number of Americans, but the mechanisms that control sleep and wakefulness are largely unknown. The Schier lab is using zebrafish to ...

  6. Priscilla Yang, PhD

    Host response to viral infection and drug discovery: dengue virus, hepatitis B and C viruses

    Investigate molecular mechanisms of dengue and hepatitis virus infection and replication; perform HTS for viral antagonists to identify host factors and pathways required for dengue virus infection ...