Keyword(s): Immunology

  1. Ronald Desrosiers, PhD

    HIV and AIDS: vaccine; persistent immune response

    Develop new strategies for blunting viral replication and bolstering the immune system’s ability to eradicate viral-infected T-cell reservoirs. 

  2. Martin Dorf, PhD

    Molecular signaling in inflammation: TNF; cytokine; autoimmune disease; T-cell

    Investigate the biochemical signaling perturbations elicited by the pro-inflammatory cytokine TNF that serve to modulate the activation of NF-кB, with a focus on TNF receptor-associated factor ...

  3. David Evans, PhD

    HIV infection and AIDS vaccine development

    Investigate new approaches for AIDS vaccine development using SIV infection of non-human primates as a model system.  

  4. Robert Paul Johnson, MD

    HIV mechanism of action and new AIDS therapies

    Gene therapy; vaccines

  5. Amitinder Kaur, MD

    AIDS pathogenesis and CMV opportunistic infection: SIV; vaccine; AIDS resistance

    AIDS modeling in non-human primates; reactivation of latent CMV in HIV-infected individuals; innate resistance to SIV-related disease progression.  

  6. Xuebin Qin, MD, PhD

    Immune modulation to treat cancer and viral infections

    CD59, the complement cascade, and disease    

  7. Arlene Sharpe, MD, PhD

    T-cell regulation and disease: chronic viral infection; autoimmunity, tumor immunotherapy, peripheral tolerance

    T cell co-stimulation and its immunoregulatory role in controlling the balance between T cell activation and tolerance.  

  8. Michael Starnbach, PhD

    Bacterial infection and acquired immunity

    T-cell response to bacterial infection, including sexually transmitted chlamydia disease

  9. Ulrich von Andrian, MD, PhD

    Adaptive immunity and leukocyte trafficking: lymphocyte activation; lymphatic system; intravital microscopy

    Study how immunological memory is produced through the orchestration of the adaptive immune response, including initiation, regulatory mechanisms, and immune cell homing to organs; harnessing of this ...

  10. Priscilla Yang, PhD

    Host response to viral infection and drug discovery: dengue virus, hepatitis B and C viruses

    Investigate molecular mechanisms of dengue and hepatitis virus infection and replication; perform HTS for viral antagonists to identify host factors and pathways required for dengue virus infection ...