Keyword(s): Aging
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Vlad Denic, PhD
Fundamental cell biological processes: autophagy, protein aggregation and aging, secretory pathways
Investigate the mechanisms of post-translational targeting pathways used to deliver membrane proteins to their appropriate cellular organelle; Define the mechanisms that lead to enhanced formation of ...
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Florian Engert, PhD
Neural basis of behaviors in vertebrates
Identify the neural circuits that control specific behaviors in vertebrates; Examine these neural circuits in molecular and cellular detail to understand how neural activity controls innate behavior.
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Walter Fontana, PhD
Information biology: principles, limits, and evolution of information processing in molecular systems
Develop, apply, and establish the concept of programs as models to represent, model, and analyze complex systems of molecular interactions underlying cellular behavior; empirically characterize and ...
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Marcia Haigis, PhD
Mitochondrial dysfunction in aging and disease: bioenergetics, metabolomics, and cell stress
Study the role of the sirtuins in metabolism, aging, and disease
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Joshua Sanes, PhD
Brain information processing and synaptic architecture
Synapses are the main information processing sites in the brain. Defects in their function underlie many neurological and behavioral disorders, and there is increasing evidence that many of these ...
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David Sinclair, PhD
Sirtuins in aging and disease: calorie restriction; mitochondria; cancer; diabetes
Study sirtuin pathways, their role in multiple diseases and their lifespan extension capabilities.
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Susan Westmoreland, VMD
Neuropathology of HIV and SIV infections and AIDS
Explore the molecular and cellular bases of neuropathologies associated with HIV and SIV infections, including encephalitis and dementia.
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Bruce Yankner, MD, PhD
Molecular mechanisms of aging and aging-related neurodegenerative diseases
Explore aging at the molecular level, employing a systems biology approach
