Harvard University Office of Technology Development Collaborative Research Opportunity Finder

1. John Blenis, PhD

   Signal transduction: nutrient and energy sensing; disease; mTOR; PI3-kinase; Ras

   Explore the diverse yet overlapping intracellular transmission signals propagated by cell surface receptors that respond to extracellular growth factors, environmental conditions, and other ...

   

2. Azad Bonni, MD, PhD

   Neuronal cell development; glioblastoma

   Investigate key intracellular signaling pathways in neuronal cell development and maturation as well as in brain tumors such as glioblastoma  

   

3. Joan Brugge, PhD

   Epithelial cell biology; mechanisms of breast and ovarian cancer development

   The biology of epithelial cells and tissues, with an emphasis on mammary gland morphogenesis and breast and ovarian cancer  

   

4. Marcia Haigis, PhD

   Mitochondrial dysfunction in aging and disease: bioenergetics, metabolomics, and cell stress

   Study the role of  the sirtuins in metabolism, aging, and disease

   

5. Peter Howley, MD

   Papillomavirus biology

   Investigate the activities of papillomavirus-encoded proteins, including the E6-mediated degradation of p53 and E2-mediated regulation of viral transcription and genome replication

   

6. Amin Kassis, PhD

   Radiolabeled small molecule prodrugs for non-invasive cancer imaging and therapy

   Development of Enzyme-Mediated Cancer Imaging and Therapy (EMCIT) as a new paradigm for noninvasive radioimaging and radiotherapy (ß- and alpha-particle emitting radionuclides) of solid ...

   

7. Galit Lahav, PhD

   The p53 tumor suppressor as a model for studying temporal dynamics of signaling networks

   Investigate protein dynamics at the single cell level; quantification of proteins in live cells using fluorescence microscopy and mathematical modeling; cellular decision-making in cancer and healthy ...

   

8. Gerhard Wagner, PhD

   NMR spectroscopy for analyzing protein structure/function relationships; small molecule screening

   Study protein structure and small molecule binding to proteins, using NMR spectroscopy and other complementary methods  

   

Research Categories

Biological Mechanisms and Pathways

Cancer

Sub-categories

1. Cell Death

   1. Apoptosis»
   2. Autophagy»
   3. test»

2. Molecular/Cellular/Viral

   1. Acquired immunity»
   2. Adaptive immunity»
   3. Alternative splicing»
   4. Angiogenesis»
   5. Anoikis»
   6. Apoptosis»
   7. Autocrine cascade»
   8. Axon guidance»
   9. Axonal transport»
   10. Bioenergetics»
   11. Biological circuitry»
   12. Blood coagulation»
   13. Cancer metabolism»
   14. Cell adhesion»
   15. Cell death»
   16. Cell differentiation»
   17. Cell division»
   18. Cell invasion»
   19. Cell migration»
   20. Cell stress»
   21. Cell-cell signaling»
   22. Cellular memory»
   23. Cellular morphogenesis»
   24. Chemoresistance»
   25. Chromosome segregation»
   26. Chromosome X inactivation»
   27. Circadian rhythm»
   28. Complement-mediated immune reaction»
   29. Development»
   30. DNA damage»
   31. DNA damage repair»
   32. DNA Replication»
   33. DNA-binding epigenetics»
   34. Drug resistance»
   35. Dynamics»
   36. Electrical signaling»
   37. Entosis»
   38. Epigenetics»
   39. Epithelial-to-Mesenchymal Transition (EMT)»
   40. Eukaryotic gene expression»
   41. Eukaryotic protein translation initiation»
   42. Eukaryotic regulatory networks»
   43. Feedback loop»
   44. Gene evolution»
   45. Gene expression»
   46. Gene function»
   47. Gene homology»
   48. Gene regulation»
   49. Genetic interactions»
   50. Genetic pathways»
   51. Genome translocation»
   52. Histone code»
   53. HIV immune response»
   54. Homing»
   55. Homologue pairing»
   56. Immune evasion»
   57. Immune response»
   58. Immune suppression»
   59. Immune tolerance»
   60. Immunity»
   61. Infectivity»
   62. Inflammation»
   63. Innate immunity»
   64. Intercellular signaling»
   65. Lumen formation»
   66. Macromolecular interaction»
   67. Mechanisms of protective immunity»
   68. Membrane fusion»
   69. Membrane permeability»
   70. Metabolism»
   71. Mitochondrial dysfunction»
   72. Mitogenic signaling»
   73. Mitosis»
   74. Molecular information processing»
   75. Morphogenesis»
   76. Mother-to-child transmission»
   77. Motor protein»
   78. mRNA export»
   79. mRNA splicing»
   80. Mucosal immunity»
   81. Mucosal transmission»
   82. Networks»
   83. Neuronal connectivity»
   84. Neuronal differentiation»
   85. Neuronal morphogenesis»
   86. Non-catalytic activity»
   87. Non-ribosomal peptide synthesis»
   88. Nuclear egress»
   89. Nuclear translocation»
   90. Nutrient stress»
   91. Oncogenic signaling»
   92. Osmotic stress»
   93. Oxidative stress»
   94. Pathogenesis»
   95. Persistent infection»
   96. Pheromone recognition»
   97. Physics and mechanics of chromosome dynamics»
   98. Protein degradation»
   99. Protein folding»
   100. Protein interactions»
   101. Protein misfolding»
   102. Protein secretion»
   103. Protein trafficking»
   104. Redox cycle»
   105. Regional immunity»
   106. Regulatory networks»
   107. Regulatory pathway»
   108. Replication»
   109. Ribosome biogenesis»
   110. Secretory pathway»
   111. Signaling network»
   112. SinR and SirR pathway»
   113. Stress response»
   114. T lymphopoiesis»
   115. T-cell activation»
   116. Thrombopoiesis»
   117. Trafficking»
   118. Trans gene regulation»
   119. Transcription»
   120. Transcription regulation»
   121. Translational control»
   122. Transvection»
   123. Viral endocytosis»
   124. Viral entry»
   125. Viral fusion»
   126. Viral replication»
   127. Viral structure»
   128. Virus infection»
   129. Virus neutralization»
   130. Virus reactivation»