Research Categories - Therapeutics

     

Related Investigators

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  1. Bruce Bean, PhD

    Neuronal electrical signaling, ion channels, pacemaking, and neuropharmacology

    Investigate the electrical firing and physiology of neuronal ion channels

  2. Jonathan Beckwith, PhD

    Study cellular processes in bacteria: protein folding, reduction and formation of protein disulfide bonds, membrane protein dynamics

    Investigate fundamental molecular processes, including protein folding and disulfide bond formation, using E. coli as a model system

  3. Howard Berg, PhD

    Bacterial Motility: Motor Response Based on Sensory Input

    The Berg lab studies the motile behavior of bacteria in order to understand how cells sense and respond to changes in their environment. Processing external cues is a problem encountered by ...

  4. John Blenis, PhD

    Signal transduction: nutrient and energy sensing; disease; mTOR; PI3-kinase; Ras

    Explore the diverse yet overlapping intracellular transmission signals propagated by cell surface receptors that respond to extracellular growth factors, environmental conditions, and other ...

  5. Joan Brugge, PhD

    Epithelial cell biology; mechanisms of breast and ovarian cancer development

    The biology of epithelial cells and tissues, with an emphasis on mammary gland morphogenesis and breast and ovarian cancer  

  6. James Chou, PhD

    NMR spectroscopy and membrane protein structure; viral ion channels; antiviral compounds

    Apply advanced technologies to the reconstitution and structural biochemistry of membrane proteins, with a focus on viral ion channels; analyze the structure of membrane proteins at the level of ...

  7. George Church, PhD

    Personal Genome Project

    Genomic DNA Sequencing Technologies; Gene Synthesis; Biofuel

  8. Jon Clardy, PhD

    Isolation and characterization of small molecule natural products; high-throughput screening for novel therapeutics

    Discovering small molecule, natural products and their biology; high throughput screening for small molecule chemicals that interfere with microbial and mammalian cell processes.  

  9. Vlad Denic, PhD

    Fundamental cell biological processes: autophagy, protein aggregation and aging, secretory pathways

    Investigate the mechanisms of post-translational targeting pathways used to deliver membrane proteins to their appropriate cellular organelle; Define the mechanisms that lead to enhanced formation of ...

  10. Ronald Desrosiers, PhD

    HIV and AIDS: vaccine; persistent immune response

    Develop new strategies for blunting viral replication and bolstering the immune system’s ability to eradicate viral-infected T-cell reservoirs.