Research Categories - Metabolism; Metabolic Disease and Aging

    

Related Investigators

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  1. Vlad Denic, PhD

    Fundamental cell biological processes: autophagy, protein aggregation and aging, secretory pathways

    Investigate the mechanisms of post-translational targeting pathways used to deliver membrane proteins to their appropriate cellular organelle; Define the mechanisms that lead to enhanced formation of ...

  2. Florian Engert, PhD

    Neural basis of behaviors in vertebrates

    Identify the neural circuits that control specific behaviors in vertebrates; Examine these neural circuits in molecular and cellular detail to understand how neural activity controls innate behavior.

  3. Walter Fontana, PhD

    Information biology: principles, limits, and evolution of information processing in molecular systems

    Develop, apply, and establish the concept of programs as models to represent, model, and analyze complex systems of molecular interactions underlying cellular behavior; empirically characterize and ...

  4. Marcia Haigis, PhD

    Mitochondrial dysfunction in aging and disease: bioenergetics, metabolomics, and cell stress

    Study the role of  the sirtuins in metabolism, aging, and disease

  5. Joshua Sanes, PhD

    Brain information processing and synaptic architecture

    Synapses are the main information processing sites in the brain. Defects in their function underlie many neurological and behavioral disorders, and there is increasing evidence that many of these ...

  6. Pamela Silver, PhD

    Systems and synthetic biology: gene expression; synthetic proteins; biofuel

    Investigate a wide spectrum of biological phenomena. Starting with gene regulation as a core theme, investigate nuclear spatial architecture, synthetic biology, epigenetics, systems biology, ...

  7. David Sinclair, PhD

    Sirtuins in aging and disease: calorie restriction; mitochondria; cancer; diabetes

    Study sirtuin pathways, their role in multiple diseases and their lifespan extension capabilities.

  8. Charles Weitz, MD, PhD

    Biological mechanisms of circadian clocks and their roles in metabolic processes

    Investigate molecular mechanisms of circadian clocks in the brain, retina, and peripheral tissues  

  9. Susan Westmoreland, VMD

    Neuropathology of HIV and SIV infections and AIDS

    Explore the molecular and cellular bases of neuropathologies associated with HIV and SIV infections, including encephalitis and dementia.  

  10. Fred Winston, PhD

    Mechanisms of eukaryotic gene expression in yeast: transcriptional regulation; chromatin structure

    Employs yeast as a model organism to study mechanisms of eukaryotic transcriptional regulation.