Research Categories - Cancer

    

Related Investigators

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  1. Adrian Salic, PhD

    Hedgehog signaling and cell-cell communication

    Post-translation modification with cholesterol; regulation of transcription      

  2. Yang Shi, PhD

    Histone demethylation and gene regulation: gene expression; epigenetics; disease

    Studies on lysine-specific demethylases and biochemical and functional aspects of histone demethylation.  

  3. Pamela Silver, PhD

    Systems and synthetic biology: gene expression; synthetic proteins; biofuel

    Investigate a wide spectrum of biological phenomena. Starting with gene regulation as a core theme, investigate nuclear spatial architecture, synthetic biology, epigenetics, systems biology, ...

  4. David Sinclair, PhD

    Sirtuins in aging and disease: calorie restriction; mitochondria; cancer; diabetes

    Study sirtuin pathways, their role in multiple diseases and their lifespan extension capabilities.

  5. Peter Sorger, PhD

    Systems biology applied to disease mechanisms and drug therapy

    Translate activity-based proteomic data and computational modeling into practical applications for cancer therapies, inflammation studies, and personalized medicine.  

  6. Kevin Struhl, PhD

    Eukaryotic Transcriptional Regulation

    Investigate basic mechanisms of gene regulation in yeast; Employ mammalian cell models of tumorigenesis to elucidate genetic changes that underlie cancer development and progression  

  7. Gerhard Wagner, PhD

    NMR spectroscopy for analyzing protein structure/function relationships; small molecule screening

    Study protein structure and small molecule binding to proteins, using NMR spectroscopy and other complementary methods  

  8. Fred Winston, PhD

    Mechanisms of eukaryotic gene expression in yeast: transcriptional regulation; chromatin structure

    Employs yeast as a model organism to study mechanisms of eukaryotic transcriptional regulation.  

  9. Chao-ting Wu, PhD

    Chromosomal homology, pairing, and segregation: mechanisms and implications for gene therapy, development, and human disease

    Explore mechanisms of maintaining genome integrity through the study of chromosomal homology, segregation, and pairing.  

  10. Priscilla Yang, PhD

    Host response to viral infection and drug discovery: dengue virus, hepatitis B and C viruses

    Investigate molecular mechanisms of dengue and hepatitis virus infection and replication; perform HTS for viral antagonists to identify host factors and pathways required for dengue virus infection ...