Research Categories - Cancer

    

Related Investigators

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  1. John Blenis, PhD

    Signal transduction: nutrient and energy sensing; disease; mTOR; PI3-kinase; Ras

    Explore the diverse yet overlapping intracellular transmission signals propagated by cell surface receptors that respond to extracellular growth factors, environmental conditions, and other ...

  2. Azad Bonni, MD, PhD

    Neuronal cell development; glioblastoma

    Investigate key intracellular signaling pathways in neuronal cell development and maturation as well as in brain tumors such as glioblastoma  

  3. Joan Brugge, PhD

    Epithelial cell biology; mechanisms of breast and ovarian cancer development

    The biology of epithelial cells and tissues, with an emphasis on mammary gland morphogenesis and breast and ovarian cancer  

  4. Philippe Cluzel, PhD

    Real-time analysis of signal transduction and genetic networks at the single cell level

    Investigating genome-wide transcriptional dynamics, and studying multi-drug resistance in bacteria.

  5. Victoria D'Souza, PhD

    Structural biology of retroviruses

    The D’Souza laboratory investigates the structural basis of retroviral replication, including the initiation of reverse transcription and translation of viral genes. Understanding the ...

  6. Vlad Denic, PhD

    Fundamental cell biological processes: autophagy, protein aggregation and aging, secretory pathways

    Investigate the mechanisms of post-translational targeting pathways used to deliver membrane proteins to their appropriate cellular organelle; Define the mechanisms that lead to enhanced formation of ...

  7. Martin Dorf, PhD

    Molecular signaling in inflammation: TNF; cytokine; autoimmune disease; T-cell

    Investigate the biochemical signaling perturbations elicited by the pro-inflammatory cytokine TNF that serve to modulate the activation of NF-кB, with a focus on TNF receptor-associated factor ...

  8. Catherine Dulac, PhD

    Molecular and neuronal basis of murine innate social behaviors

    Study neuronal circuits in the mouse involved with pheromone signaling in terms of their development, processing, architecture, and function; investigate the role genomic imprinting role in mammalian ...

  9. Daniel Finley, PhD

    Ubiquitin-dependent protein degradation and the proteasome: mechanisms and coordination; architecture; role in disease

    Study of proteasome activity and its relationship to diseases caused by proteinopathies.

  10. Jeremy Gunawardena, PhD

    Experimental and theoretical analysis of signal transduction: EGF signaling, drug efficacy, phosphorylation states, microfluidics, formalized biology language

    Investigate the dynamics of signal transduction, from a mechanistic and practical perspective. Describe at a fundamental level the input/output transformation that connects external signals to ...