Research Categories - Infectious Disease
Investigate the activities of papillomavirus-encoded proteins, including the E6-mediated degradation of p53 and E2-mediated regulation of viral transcription and genome replication
HIV mechanism of action and new AIDS therapies
Gene therapy; vaccines
AIDS pathogenesis and CMV opportunistic infection: SIV; vaccine; AIDS resistance
AIDS modeling in non-human primates; reactivation of latent CMV in HIV-infected individuals; innate resistance to SIV-related disease progression.
Chromosome dynamics across kingdoms
Investigation of the molecular and physical underpinnings of basic chromosomal processes.
Bacterial biofilm and Bacillus subtilis biology
Dr. Richard Losick’s laboratory investigates the mechanisms of bacterial biofilm formation and disassembly and applies this knowledge to antimicrobial development, clean water supply, protein ...
Immune modulation to treat cancer and viral infections
CD59, the complement cascade, and disease
Intracellular cargo movement: the role of molecular motors
Explore the role of dynein in molecular cargo transport
T-cell regulation and disease: chronic viral infection; autoimmunity, tumor immunotherapy, peripheral tolerance
T cell co-stimulation and its immunoregulatory role in controlling the balance between T cell activation and tolerance.
Bacterial infection and acquired immunity
T-cell response to bacterial infection, including sexually transmitted chlamydia disease
Single molecule imaging for uncovering molecular mechanisms of action: biologic and therapeutic analysis
Dr. van Oijen’s research utilizes single molecule imaging for uncovering molecular mechanisms of action pertaining to cell fusion of enveloped viruses, DNA replication fork dynamics, and ...
Antiviral compound development (small molecule and biologicals)
- Antibiotic resistance»
- Bacillus subtilis»
- Escherichia coli (E. coli)»
- Gram-negative bacteria»
- Gram-positive bacteria»
- mar operon»
- Opportunistic pathogen»
- Proteus mirabilis»
- Staphylococcus aureus (S. aureus)»
- Viral structure»
- Virus entry»
Non-HIV Virus infections