Research Categories - Disease Mechanisms

    

Related Investigators

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  1. Bruce Bean, PhD

    Neuronal electrical signaling, ion channels, pacemaking, and neuropharmacology

    Investigate the electrical firing and physiology of neuronal ion channels

  2. John Blenis, PhD

    Signal transduction: nutrient and energy sensing; disease; mTOR; PI3-kinase; Ras

    Explore the diverse yet overlapping intracellular transmission signals propagated by cell surface receptors that respond to extracellular growth factors, environmental conditions, and other ...

  3. Azad Bonni, MD, PhD

    Neuronal cell development; glioblastoma

    Investigate key intracellular signaling pathways in neuronal cell development and maturation as well as in brain tumors such as glioblastoma  

  4. Joan Brugge, PhD

    Epithelial cell biology; mechanisms of breast and ovarian cancer development

    The biology of epithelial cells and tissues, with an emphasis on mammary gland morphogenesis and breast and ovarian cancer  

  5. Constance Cepko, PhD

    Retina development and pathophysiology

    Investigate the mechanisms of the development of different retinal cell types derived from multipotent retinal progenitor cells with a focus on photoreceptor cells; study the pathological loss of ...

  6. James Chou, PhD

    NMR spectroscopy and membrane protein structure; viral ion channels; antiviral compounds

    Apply advanced technologies to the reconstitution and structural biochemistry of membrane proteins, with a focus on viral ion channels; analyze the structure of membrane proteins at the level of ...

  7. George Church, PhD

    Personal Genome Project

    Genomic DNA Sequencing Technologies; Gene Synthesis; Biofuel

  8. Jon Clardy, PhD

    Isolation and characterization of small molecule natural products; high-throughput screening for novel therapeutics

    Discovering small molecule, natural products and their biology; high throughput screening for small molecule chemicals that interfere with microbial and mammalian cell processes.  

  9. Philippe Cluzel, PhD

    Real-time analysis of signal transduction and genetic networks at the single cell level

    Investigating genome-wide transcriptional dynamics, and studying multi-drug resistance in bacteria.

  10. Victoria D'Souza, PhD

    Structural biology of retroviruses

    The D’Souza laboratory investigates the structural basis of retroviral replication, including the initiation of reverse transcription and translation of viral genes. Understanding the ...